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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21588 | Olomoucine | ERK , CDK | |
Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an... | |||
T4746 | Purine | 7H-Imidazo(4,5-d)pyrimidine | Others , Endogenous Metabolite |
Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f... | |||
TNU0909 | 1,9-Dihydro-9-methyl-6H-purin-6-one | ||
1,9-Dihydro-9-methyl-6H-purin-6-one belongs to Heterocyclic Compounds - Purines. | |||
T22409 | Proguanil | chloroguanide,chlorguanide | Others |
Proguanil, a prophylactic antimalarial drug, inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of pyrimidines and purines, which are essential for DNA synthesis and cell multiplication... | |||
TNU1134 | 7-benzyl-3-methylxanthine | ||
7-benzyl-3-methylxanthine belongs to Heterocyclic Compounds - Purines. | |||
TNU1133 | 1,7-Dibenzyl-3-methylxanthine | ||
1,7-Dibenzyl-3-methylxanthine belongs to Heterocyclic Compounds - Purines. | |||
TNU0907 | 6-Chloro-9-methyl-9H-purine | ||
Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Electrophiles | |||
TNU1262 | 1H-Imidazo[4,5-d]pyridazin-7-amine | ||
1H-Imidazo[4,5-d]pyridazin-7-amine belongs to Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases. | |||
TNU0908 | 9-Methyladenine | ||
Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleophiles | |||
TNU1104 | 6-Chloro-2-(trifluoromethyl)-9H-purine | ||
Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases; Multi-functional; Scaffolds and Templates | |||
TNU0611 | 4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine | ||
Heterocyclic compound –purines, intermediate and building block; Used for modified nucleosides and nucleic acids | |||
TNU0900 | 2-Amino-6-ethoxypurine | ||
Heterocyclic Compounds –Purines; Intermediates and Building Blocks - Nucleoside bases | |||
T63240 | Lometrexol disodium | ||
Lometrexol (DDATHF) disodium is a potent inhibitor of human serine hydroxymethyltransferase 1/2 (hSHMT1/2) and antifolate, which reduces the activity of glycinamide ribonucleotide formyltransferase (GARFT) without causin... | |||
T35413 | (6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride) | ||
(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. Its metabolites participate in... |