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Search Results for " pan-caspase "

9

Compounds

Cat No. Product Name Synonyms Targets
T7020 Z-VAD-FMK Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD Caspase
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases with irreversible properties. Z-VAD-FMK binds to activated caspases, thereby inhibiting apoptosis.
T0282 Q-VD-OPH Quinoline-Val-Asp-Difluorophenoxymethylketone Caspase , HIV Protease
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
T6826 Emricasan PF 03491390,IDN-6556 Influenza Virus , Caspase
Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan a...
T21293 MX1013 MX 1013,MX-1013
MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.
T13445 (R)-Q-VD-OPh (R)-Quinoline-Val-Asp-Difluorophenoxymethylketone,(R)-QVD-OPH Others
(R)-Q-VD-OPh is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible inhibitor of pan-caspase, with potent antiapoptotic properties.
T80624 Ac-VAD-CHO Ac-Val-Ala-Asp-CHO Caspase
Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of cytochrome c in cells subjected to hypoxia [1].
T39586 Cantrixil TRX-E-002-1
Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an increase in phosphorylated c-Jun levels, leading to caspase-mediated apoptosis in ovarian cancer cells...
T69200 CGP74514A
CGP74514A is a CDK1 inhibitor with potential anticancer activity. In U937 cells, CGP74514A - induced apoptosis (5 microM) became apparent within 4 hr and approached 100% by 24 hr. The pan- caspase inhibitor Boc-fmk and t...
T75010 TD1092
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB...
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