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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16766 | Ro 08-2750 | ||
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2... | |||
T11861 | LM11A-31 dihydrochloride | Others | |
LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni... | |||
T12384 | PD 90780 | Others | |
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC1... | |||
T28206 | NSC49652 | NSC 49652,NSC-49652 | Apoptosis |
NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model. | |||
TP2278 | NTR 368 | Others | |
cytoplasmic peptide of the neurotrophin receptor p75NTR | |||
T75831 | NTR 368 TFA | ||
NTR 368 TFA, a peptide derived from the p75 neurotrophin receptor (p75NTR) and corresponding to residues 368-381 of the human receptor, exhibits a helix-forming propensity in the presence of micellar lipid. It is a poten... | |||
T76813 | Bedinvetmab | ||
Bedinvetmab (ZTS-00508841), a canine monoclonal antibody (mAb) designed to target nerve growth factor (NGF), prevents NGF from interacting with its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin rec... | |||
T35365 | LM11A-31 | LM11A-31 | Others |
LM11A-31 is a useful organic compound for research related to life sciences. The catalog number is T35365 and the CAS number is 289475-77-0. | |||
T74097 | THX-B | ||
THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3]. |