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Search Results for " opioid "

20

Compounds

Cat No. Product Name Synonyms Targets
T12314 Opioid receptor modulator 1 Opioid Receptor
Opioid receptor modulator 1 is a modulator of opioid receptor.
T62673 Mu opioid receptor antagonist 5
Mu opioid receptor antagonist 5 (compound NAP) is a selective mu opioid receptor (MOR) antagonist that crosses the blood-brain barrier (EC50: 1.14 nM, Ki: 0.37 nM). Mu opioid receptor antagonist 5 can be used to study op...
T62766 Mu opioid receptor antagonist 2
Mu opioid receptor antagonist 2 (compound 25) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM). Mu opioid receptor antagonist 2 can be used...
T62768 Mu opioid receptor antagonist 4
Mu opioid receptor antagonist 4 (compound 31) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.38 nM, EC50: 0.38 nM). Mu opioid receptor antagonist 2 can be used...
T79430 μ opioid receptor agonist 3 Opioid Receptor
Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain management and neuropsychiatric disorders [1].
T62767 Mu opioid receptor antagonist 3
Mu opioid receptor antagonist 3 (compound 26) is a potent and selective mu opioid receptor (MOR) antagonist that penetrates the blood-brain barrier (Ki: 0.24 nM, EC50: 0.54 nM). Mu opioid receptor antagonist 2 can be use...
T62025 μ opioid receptor agonist 2
μ opioid receptor agonist 2 (Compound H-3)is a MOR receptor agonist. μ opioid receptor agonist 2 can be used for the research of pain and pain related diseases.
T79431 Mu opioid receptor antagonist 7 Opioid Receptor
Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting µ-opioid receptor (µOR) antagonist with an inhibitory concentration (IC50) of 29 ± 3.0 nM. It is valuable for pain and opioid use ...
T62268 μ opioid receptor agonist 1
μ opioid receptor agonist 1 (Compound H-1a) is an optically pure oxyheterocyclic substituted pyrroloxypyrazole derivative and an MOR receptor agonist that can be used in the study of pain and pain-related disorders.
T61901 σ1 Receptor/μ Opioid receptor modulator 1
σ 1 Receptor/ μ Opioid receiver modulator 1 (Compound 44) is an effective σ 1 receptor antagonist (Ki=1.86 nM) and μ Opioid receptor agonists (Ki=2.1 nM). Opioid receptor modulator 1 shows potent analgesic activity, and ...
T6S1010 Allomatrine Others
Allomatrine is a natural product from Sophora alopecuroides L. Allomatrine, when given i.c.v., may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord.
T7748 Dermorphin TFA Others , Opioid Receptor
Dermorphin TFA is a new class of opioids-like peptides
T4691 Asimadoline hydrochloride EMD-61753 hydrochloride Opioid Receptor
Asimadoline hydrochloride (EMD-61753 hydrochloride) is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline hydrochloride has also been shown to be used in the treatment of irritable bowel s...
T9459 GR103545 Others
GR103545 is a selective agonist of the κ-opioid receptor, which is a radiotracer that can be used as in vivo imaging.
T4407 SR17018 Opioid Receptor
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
T4386 PZM21 Opioid Receptor
PZM21 is an effective and selective μ opioid receptor agonist (EC50: 1.8 nM).
T8992 BMS986188 Opioid Receptor
BMS986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor.
TP1832 Gluten Exorphin C Opioid Receptor
Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pe...
T1242 Alvimopan Opioid Receptor
Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid...
T8991 BMS986187 Opioid Receptor
BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
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