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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6599 | N6-methyladenosine | N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A | Others , Influenza Virus , Endogenous Metabolite |
N6-methyladenosine (NSC-29409) is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological ma... | |||
T7138 | FB23-2 | Apoptosis , Others | |
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM). | |||
T74474 | M7Gpppm6AmpG ammonium | ||
M7Gpppm6AmpG ammonium, a trinucleotide mRNA 5’ cap analog, facilitates in vitro RNA synthesis [1]. | |||
T74473 | M7Gpppm6AmpG | ||
m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1]. | |||
T8874 | FB23 | Others | |
FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.) | |||
T67930L | CWI1-2 HCL | Apoptosis | |
CWI1-2 HCL is an effective IGF2BP2 inhibitor, which can induce apoptosis and differentiation by binding IGF2BP2 and inhibiting its interaction with M6A-modified target transcription, and has therapeutic effects on leukem... | |||
T37198 | Ethyl LipotF | ||
Selective FTO inhibitor (IC50 = 0.81 μM). Exhibits >30-fold selectivity for FTO over ALKBH2, 3 and 5 and >100-fold selectivity over PHD2 and JMJD2A. Increases levels of modified N6-methyladenosine (m6A) in HeLa cells in ... | |||
T67930 | CWI1-2 | Apoptosis | |
CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and can induce apoptosis and differentiation. | |||
T37447 | UZH1 | UZH1 | |
UZH1 is a racemate of UZH1a and UZH1b. UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1b (IC50=28 μM) is essentially inactive. UZH1 can be used for epitranscriptomic modulation of cellular p... |