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Search Results for " k63 "

6

Compounds

Cat No. Product Name Synonyms Targets
T8931L ICCB-19 hydrochloride ICCB-19 HCl(750621-52-4 free base) Apoptosis , Others , Autophagy , RIP kinase
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal dom...
T71573 STK630921
STK630921 is a blocker of IL-17A binding to the IL-17A receptor (IL-17RA).
T1757 ML-323 ML323 DUB
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (I...
T82413 FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 AUTACs
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 serves as a linker for AUTAC4, a compound comprising a p-fluorobenzylguanine (FBnG) unit and a phenylindole moiety. This construction is capable of inducing K63-linked polyub...
T82632 Cys-C-cGMP AUTACs
Cys-C-cGMP serves as an autophagy tag for AUTACs (autophagy-targeting chimeras). It enhances K63-linked ubiquitination of mitochondria within HeLa cells [1].
T74018 CGMP-HTL
cGMP-HTL, an autophagy-targeting chimera (AUTAC), consists of a HT-ligand, a linker, and a Cys-S-cGMP (autophagy tag), designed to enhance K63-linked ubiquitination of mitochondria. This novel clearance strategy features...
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