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Search Results for " hydratase "

7

Compounds

Cat No. Product Name Synonyms Targets
T11337 Fumarate hydratase-IN-1 Others
Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM. Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor.
T11336 Fumarate hydratase-IN-2 sodium salt Others
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor ( K i =4.5 μM). Fumarate hydratase-IN-2 sodium salt has nutrient-dependent cytotoxicity [1].
T6759 AP-III-a4 ENOblock Glucokinase
AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.
T5564 Tricarballylic acid β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,Carballylic acid,Propane-1,2,3-tricarboxylic acid aconitase , Mitochondrial Metabolism
Tricarballylic acid (Carballylic acid) is an inhibitor of aconitase.
T4766 3-Methylglutaric acid Endogenous Metabolite
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...
T71901 MP-1
MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1.
T78467 Trans-10-Heptadecenoic acid
Trans-10-heptadecenoic acid, a trans-fatty acid, undergoes polymerization to form polyhydroxy-chain alkanoates via the enzymatic actions of 2,4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the enzyme's ...
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