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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1812 | KX1-004 | KX1 004,KX1004 | Src |
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK. | |||
T7683 | Adenosine amine congener | ADAC | Adenosine Receptor |
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. | |||
T33815 | ORC-13661 HCl | ORC 13661,BPN13661,ORC13661,ORC-13661,BPN 13661,BPN-13661 | |
Orc-13661 (BNP-13661) is a potent and well-tolerated oral active protective agent for the prevention of aminogrogycoside-induced hearing loss. | |||
T61594 | BF844 | ||
BF844 is a chemical compound that demonstrates the ability to mitigate hearing loss in individuals with Usher Syndrome Type III (USH3) caused by the CLRN1 mutation (specifically N48K). One of its mechanisms of action is ... | |||
T72224 | NK1 receptor antagonist 2 | ||
NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research. | |||
T78217 | (R)-Azasetron besylate | SENS-401 | Phosphatase |
(R)-Azasetron besylate (SENS-401), an orally active calcineurin inhibitor, has been shown to mitigate cisplatin-induced hearing loss and cochlear damage [1][2]. | |||
T65440 | Sodium Thiosulfate Pentahydrate | ||
Sodium thiosulfate (Pentahydrate) is an antioxidant and antifungal. Sodium thiosulfate protects against cisplatin-induced hearing loss in children and is not associated with serious adverse events attributed to its use[3... | |||
T81664 | NMB-1 | ||
NMB-1, a conopeptide analogue, selectively inhibits sustained mechanically activated currents in sensory neurons with an IC50 of 1 μM, attenuating mechanical pain. It is utilized in research pertaining to hearing and pre... | |||
T80852 | VRT-534 | ||
VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. It has pot... |