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Search Results for " htlr2/6 "

4

Compounds

Cat No. Product Name Synonyms Targets
T3502 C29 TLR
C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.
T15017 CU-T12-9 TLR
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...
T16123 MMG-11 Others
MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotox...
T60763 MMG-11 quarterhydrate
MMG-11 quarterhydrate is a potent and selective antagonist of human TLR2 which inhibits both TLR2/1 and TLR2/6 signaling with low cytotoxicity. The IC 50 s of MMG-11 quarterhydrate for Pam 3 CSK 4 -induced hTLR2/1 and f...
TargetMol