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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21992 | Vacuolin-1 | PI3K , Autophagy | |
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ... | |||
TP1915 | Boc-MLF | Others | |
Antagonist of formyl peptide receptor 1 (FPR1). Reduces superoxide production induced by fMLF with an EC50 of 0.63 μM. Almost completely blocks fMLF-stimulated primary granule exocytosis. | |||
T69194 | Endosidin5 | ||
Endosidin5 is a novel exocytosis inhibitor. | |||
T31790 | FFN200 dihydrochloride | FFN200 HCl,FFN200,FFN 200,FFN-200 | |
FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue. | |||
T14829 | Bromoenol lactone | (6E)-Bromoenol lactone | Phospholipase |
Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ infl... | |||
T81035 | TAT-NSF222 Fusion Peptide | ||
TAT-NSF222 Fusion Peptide is a bifunctional polypeptide comprising a TAT domain, facilitating cellular uptake via macropinocytosis, and an NSF domain, which acts as an inhibitor of N-ethylmaleimide-sensitive factor (NSF)... | |||
TP1576 | SNAP-25 187-203 | ||
This amino acids187 to 203 fragment is derived from the C-terminal helix of synaptosomal-associated protein of 25 kDa (SNAP-25). This peptide is able to rescue exocytosis from botulinum neurotoxin E (BoNT/E)-treated cell... | |||
T61265 | Exo2 | ||
Exo2 is a secretion inhibitor that hinders the trafficking of Shiga toxin from endosomes to the trans-Golgi network. It inhibits the exit of secretory cargo from the endoplasmic reticulum (ER) and disrupts the Golgi appa... | |||
T76549 | TAT-NSF700scr | ||
TAT-NSF700scr comprises the complete TAT domain and a glycine linker, succeeded by the NSF amino acids arranged randomly. It serves as a control peptide, ineffective in inhibiting SNARE-mediated exocytosis [1] [2]. | |||
T75793 | ω-Agatoxin IVA TFA | ||
ω-Agatoxin IVA TFA is a potent selective inhibitor of P/Q type Ca2+ (Cav2.1) channels, exhibiting IC50 values of 2 nM for P-type and 90 nM for Q-type channels. It effectively inhibits glutamate exocytosis and calcium inf... |