Home Tools
Log in
Cart

Search Result

Search Results for " epoxyketone "

3

Compounds

Cat No. Product Name Synonyms Targets
T6830 Epoxomicin BU-4061T,BU-4061T,Aids010837 Apoptosis , Proteasome
Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited...
T6041 Oprozomib PR-047,ONX 0912 Proteasome , Autophagy
Oprozomib (PR-047) (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome β5(IC50=36 nM)/LMP7(IC50=82 nM), is orally bioavailable. Oprozomib also has potential antineoplastic activity.
T16568 PR-924 Proteasome
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-92...
TargetMol