Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 722.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 1,820.00 |
Description | PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites. |
Targets&IC50 | LMP2:8.2 μM, LMP7:22 nM |
Molecular Weight | 618.72 |
Formula | C37H38N4O5 |
CAS No. | 1416709-79-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PR-924 1416709-79-9 Proteases/Proteasome Ubiquitination Proteasome PR924 PR 924 inhibitor inhibit