3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14965 | Ciliobrevin D | ATPase , Hedgehog/Smoothened | |
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ... | |||
T15183 | Dynarrestin | Hedgehog/Smoothened | |
Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl... | |||
T35548 | Dynapyrazole A | Dynamin | |
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. |