7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60028 | MM41 | DNA/RNA Synthesis | |
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line. | |||
T21648 | CP-31398 dihydrochloride | CP 31398 dihydrochloride | p53 |
CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. | |||
T31364 | Dehydelone | KOS1584,SK-10088,KOS-1584,R-1645,SK10088,R1645 | |
Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer. | |||
T32419 | KRAS4b-PDEδ stabilizer C19 | ||
KRAS4b-PDEδ stabilizer C19 is a stabilizer of the KRAS4b-PDEδ complex which decreases the proliferation of colorectal cancer cells, and increases apoptosis via decreased activation of oncogenic KRAS4b signaling. | |||
T75573 | Taccalonolide E | ||
Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis . | |||
T61024 | PK9327 | ||
PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations. | |||
T81285 | RGB-1 | ||
RGB-1, a polycyclic aromatic hydrocarbon, functions as a stabilizer of RNA G-quadruplexes and may inhibit RNA translation while decreasing NRAS proto-oncogene expression in breast cancer cells [1]. |