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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6514 | Glasdegib | PF-04449913 | Hedgehog/Smoothened , Smo |
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2. | |||
T71455 | Glasdegib hydrochloride | ||
Glasdegib hydrochloride is a small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. | |||
T80568 | Casdozokitug | SRF-388 | |
Casdozokitug (SRF-388) is an IgG1κ monoclonal antibody that specifically targets interleukin-27 (IL-27) [1]. | |||
T27966 | M1000907 | M-1000907,M 1000907 | |
M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02398 | ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His) | Legionella pneumophila | E. coli |
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. | |||
TMPH-01375 | Gasdermin-C Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Gasdermin-C Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 61.7 kDa and the accession number is Q9BYG8. | |||
TMPH-02670 | Gasdermin-A3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Precursor of a pore-forming protein involved in the transition from catagen to telogen at the end of hair follicle morphogenesis. This form constitutes the precursor of the pore: upon cleavage, the released N-terminal mo... | |||
TMPH-01376 | Gasdermin-C Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Gasdermin-C Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.7 kDa and the accession number is Q9BYG8. | |||
TMPH-02671 | Gasdermin-D Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-term... | |||
TMPH-01374 | Gasdermin-B Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Gasdermin-B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.2 kDa and the accession number is Q8TAX9. | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... |