araf — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25055	Alpha-RA-F	α RA F,alphaRAF,α-RA-F,αRAF
	alpha-RA-F can modulate collagen synthesis and matrix metalloproteinases (MMPs) expression levels by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.
T16989	Tarafenacin D-tartrate	SVT-40776 D-tartrate	Others
	Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.		Others
T63333	Uplarafenib	B-Raf IN 10	Raf
	Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 in the range of 50-100 nM.B-Raf IN 10 has antitumor activity that may affect cell proliferation and differentiation did not, and can be used to study soli...		Raf
T20774	Sarafloxacin	A-56620,A 56620,A56620	Antibacterial , Antibiotic
	Sarafloxacin (A56620) has antibacterial activities against Gram-positive and Gram-negative bacteria.		Antibacterial , Antibiotic
T1107	Sarafloxacin hydrochloride	Sarafloxacin HCl,A-56620 (hydrochloride),A-56620 HCl	Antibacterial , Antibiotic
	Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.		Antibacterial , Antibiotic
T63644	Exarafenib	RAF/KIN_2787	Raf , p38 MAPK
	Exarafenib (RAF/KIN_2787) is a potent and orally available pan-RAF inhibitor.Exarafenib has antitumor activity and acts by inhibiting downstream MAPK pathway signaling.Exarafenib is used in cancer research.		Raf , p38 MAPK
T5634	Belvarafenib		Raf
	Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.		Raf
T64194	Belvarafenib TFA
	Belvarafenib TFA (HM95573 TFA) is a potent and broadly available rapidly accelerating inhibitor of fibrosarcoma kinase (RAF) that acts on B-RAF (IC50: 56 nM), B-RAFv600E (IC50: 7 nM) and C-RAF (IC50: 5 nM).
T25919	Paraflutizide	LD3612,LD 3612,Paraflutizida,LD-3612
	Paraflutizide is a thiazide analog antihypertensive.
T16990	Tarafenacin	SVT-40776	Others
	Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.		Others
T75807	Sarafotoxin S6a TFA
	Sarafotoxin S6a TFA, an analogue of sarafotoxin, functions as an endothelin receptor agonist with an ET_A/ET_B selectivity profile akin to Endothelin-3. It demonstrates an EC_50 of 7.5 nM in stimulating the pig coronary ...
TP2120	Sarafotoxin S6c
	Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
TP2290	Sarafotoxin S6b		Others
	non-selective endothelin receptor agonist		Others
T64746	Paraffin liquid
	Paraffin liquid is a useful organic compound for research related to life sciences and the catalog number is T64746.
T80240	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype of G-protein coupled receptors involved in mediating thrombin...
T81176	Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2
	Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biologically active peptide. Structure-activity studies of the thrombin receptor-tethered ligand SFLLRNP underscored the pivotal role of the Phe-2-phenyl group in receptor r...
T76302	[Lys4] Sarafotoxin S6c
	[Lys4] Sarafotoxin S6c, an analogue of sarafotoxin, serves as a potent, partial agonist of the endothelin receptor, inducing contraction in pig coronary artery with an effective concentration (EC 50) of 1.5 nM [1].
TP2119	Sarafotoxin S6a
	Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
T11898	LXH254		Raf
	LXH254 is a potent C-Raf and B-Raf inhibitor.		Raf