14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6716 | Valsartan | Diovan,Tareg,CGP 48933 | RAAS |
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension. | |||
T2318 | Sacubitril/Valsartan | Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 | Apoptosis , RAAS , Neprilysin |
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. | |||
T20564 | Valsartan benzyl ester | Valsartan impurity B,Valsartan related compound C | |
Valsartan benzyl ester is a intermediate of Valsartan. | |||
T67848 | Valsartan Methyl Ester | RAAS | |
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM. | |||
T35725 | 4-hydroxy Valsartan | ||
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood. | |||
T13283 | Valsartan Ethyl Ester | Others | |
Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure. | |||
T13282 | Valsartan-d9 | CGP-48933 D9 | Others |
Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure. | |||
T68890 | Desvaleryl Valsartan | ||
Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions. | |||
T4200 | Sacubitril hemicalcium salt | AHU-377 (hemicalcium salt),AHU377 calcium salt | Neprilysin |
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... | |||
T20126 | Losartan potassium impurity E | L-158507,L 158507,L158507 | |
Losartan potassium impurity E is a compound of Valsartan impurity. | |||
T4574L | Sacubitril sodium | AHU377,AHU-377,LCZ696,AHU 377 | |
Sacubitril is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. | |||
T19113 | 2S,4R-Sacubitril | Others | |
2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure. | |||
T19111 | 2R,4R-Sacubitril | Others | |
2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure. | |||
T19622 | (Z)2S,4R-Sacubitril | Others | |
(Z)2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure. |