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Search Results for " urocortin "

18

Compounds

Cat No. Product Name Synonyms Targets
TP1020L Urocortin (rat) acetate Urocortin (rat) acetate (171543-83-2 Free base) CRFR
Urocortin (rat) acetate is an agonist of endogenous CRFR with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively. Urocortin (rat) acetate is a neuropeptide.
TP1021 Urocortin, human Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I CRFR
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
TP1020 Urocortin, rat Urocortin (Rattus norvegicus),Rat urocortin
Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.
TP2159 Urocortin, rat TFA (171543-83-2 free base) Urocortin (Rattus norvegicus) (TFA),Rat urocortin TFA,Urocortin, rat TFA Others
Urocortin, rat TFA is a neuropeptide and a potent endogenous CRFR agonist (Kis: 0.97 nM, 1.5 nM, and 13 nM for mouse CRF2β, rat CRF2α, and human CRF1).
TP1504 Urocortin III, mouse TFA (357952-10-4 free base) Urocortin III, mouse TFA
Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response sys...
TP1860 Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.
T35814 Urocortin III (human) (trifluoroacetate salt)
Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin II...
T36373 Urocortin II (mouse) (trifluoroacetate salt)
Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II...
TP1649 Urocortin III, mouse
Mouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.
TP1557 Urocortin II, human TFA
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. Human urocortin II exhibits mild motor-suppressive effects and delayed anxiolytic-l...
T76180 Urocortin III (human)
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system ...
T76492 (Tyr0)-Urocortin, rat
(Tyr0)-Urocortin, rat, serves as a high-affinity agonist for both corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2), demonstrating inhibitory binding constants (Ki) of 1-2 nM [1].
T75892 Urocortin, rat TFA
Urocortin (Rattus norvegicus) TFA, a neuropeptide and potent endogenous CRFR agonist, demonstrates affinity with Ki values of 13 nM for human CRF1, 1.5 nM for rat CRF2α, and 0.97 nM for mouse CRF2β, indicating its signif...
T76127 Urocortin II, mouse
Urocortin II, mouse, is a selective and potent endogenous peptide agonist for the type-2 corticotropin-releasing factor (CRF2) receptor, displaying K_i values of 0.66 nM for CRFR2 and >100 nM for CRFR1, signifying its hi...
T76025 Urocortin III, mouse TFA
Urocortin III, mouse TFA, a corticotropin-releasing factor (CRF)-related peptide, preferentially activates CRF-R2 [1], demonstrating its significant role in the behavioral stress response system as a component of Urocort...
T76319 Urocortin III (mouse) (free acid)
Urocortin III (mouse) (free acid), a selective agonist with high affinity for the CRF2 receptor, significantly inhibits gastric emptying while not affecting colonic transit [1] [2].
TP2009 K41498 K 41498
Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-exp...
T83674 K 41498 TFA
K 41498 is a selective peptide antagonist targeting both corticotropin-releasing factor receptor 2α (CRF2α) and CRF2β, demonstrating high affinity with Kis of 0.66 and 0.62 nM, respectively, in HEK293 cells expressing th...
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