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Search Results for " unc569 "

3

Compounds

Cat No. Product Name Synonyms Targets
T21302 UNC569 UNC 569 TAM Receptor
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...
T21302L UNC 569 hydrochloride UNC 569 hydrochloride (1350547-65-7 Free base) TAM Receptor , TAM Receptor
UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydr...
T21301 Lesinurad sodium Lesinurad,RDEA 594,RDEA-594,RDEA594
UNC569, the first small-molecule MER inhibitor, inhibits Mer activation and downstream signaling through ERK1/2 and AKTwith. UNC569 shows efficacy against acute lymphoblastic leukemia in vitro and in vivo.
TargetMol