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Cat No. | Product Name | Synonyms | Targets |
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T79429 | Tubulin polymerization-IN-50 | ||
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell cycle arrest at the G2/M phase [1]. | |||
T60902 | Tubulin polymerization-IN-31 | ||
Tubulin polymerization-IN-31 (Compound 4c) has antitumor activity and induces apoptosis of cancer cell. Tubulin polymerization-IN-31 is an inhibitor of tubulin polymerization with an IC 50 value of 3.64 μM [1]. | |||
T60735 | Tubulin polymerization-IN-22 | ||
Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22 is an inhibitor of tubulin polymerization (IC 50 = 8.1 μM) [1]. | |||
T60600 | Tubulin polymerization-IN-14 | ||
Tubulin polymerization-IN-14 (Compound 20a) is a tubulin polymerization inhibitor (IC 50 = 3.15 μM) that exhibits potent anti-vascular and anticancer activities including cancer cell apoptosis [1]. | |||
T36358 | Diminutol | ||
Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization ... | |||
T62040 | Tubulin polymerization-IN-30 | ||
Tubulin polymerization-IN-30 (compound 6e) is a potent inhibitor of Tubulin polymerization. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin po... | |||
T60802 | Tubulin polymerization-IN-2 | ||
Tubulin Polymerization-IN-2 is a powerful anticancer agent that targets β-tubulin, exhibiting an IC 50 of 0.92 μM. It demonstrates promising efficacy against a range of cancer cell lines including leukemia, non-small cel... | |||
T83819 | 2'-O-Methylguanosine-5'-O-triphosphate sodium | 2'-methyl GTP,2'-O-methyl GTP | |
2’-O-Methylguanosine-5’-O-triphosphate (2’-methyl GTP) acts as an inhibitor targeting the hepatitis C virus (HCV) non-structural protein 5B (NS5B; with an IC50 of 3.5 µM), and serves as an active metabolite of the prodru... |