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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6708 | Tolcapone | Tasmar,Ro 40-7592 | Apoptosis , Beta Amyloid , Transferase |
Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa. | |||
T13181 | Tolcapone D7 | Ro 40-7592 D7 | Transferase |
Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of COMT. | |||
T10119 | 3-O-Methyltolcapone | Ro 40-7591 | Transferase |
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of Parkinson's disease. | |||
T10118 | 3-O-Methyltolcapone D7 | Ro 40-7591 D7 | Transferase |
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier... | |||
T28593 | Ro 61-1448 | Ro-61-1448,Ro 611448 | |
Ro 61-1448 is a metabolite of tolcapone, a catechol-O-methyltransferase inhibitor. | |||
T11207 | Entacapone sodium salt | Others | |
Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapo... |