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3-O-Methyltolcapone D7

Catalog No. T10118 CAS T10118

Synonyms: Ro 40-7591 D7

3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of Parkinson's disease.

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3-O-Methyltolcapone D7 Chemical Structure

3-O-Methyltolcapone D7, CAS T10118

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Ro 40-7591 D7
Molecular Weight	294.31
Formula	C15H6D7NO5
CAS No.	T10118

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Jorga K, et al. Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase. Br J Clin Pharmacol. 1999 Oct;48(4):513-20. 2. Ceravolo R, et al. 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse. 2002 Mar 1;43(3):201-7.

Related Products

Related compounds with same targets

P-3FAX-Neu5Ac Sinbaglustat (E)-Daporinad Serotonin Tolcapone Tolcapone D7 Nitecapone JNJ-DGAT2-A

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Keywords

3-O-Methyltolcapone D7 T10118 Metabolism Transferase Ro 40-7591 D7 3OMethyltolcapone D7 3-O-Methyltolcapone D-7 3 O Methyltolcapone D7 inhibitor inhibit

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