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Search Results for " tofacitinib "

12

Compounds

Cat No. Product Name Synonyms Targets
T6321 Tofacitinib Tasocitinib,CP-690550 ROCK , Apoptosis , JAK , Src
Tofacitinib (Tasocitinib) is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis.
T2398 Tofacitinib Citrate CP-690550 citrate,Tasocitinib citrate,Tofacitinib (CP-690550) Citrate Apoptosis , Influenza Virus , JAK , Antibacterial , Antifungal
Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).
T37638 Tofacitinib metabolite-1
Tofacitinib metabolite-1, a derivative of Tofacitinib, which is a JAK inhibitor, is employed in studies focused on the pharmacokinetics and metabolism of tofacitinib[1][2].
T13426 (3R,4S)-Tofacitinib Others
(3R,4S)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).
T13427 (3S,4R)-Tofacitinib Others
(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).
T70168 Tofacitinib HCl
Tofacitinib, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes ...
T13426L (3S,4S)-Tofacitinib Others
(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.
T69958 Tofacitinib maleate
Tofacitinib, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes ...
T72406 Tofacitinib Prodrug-1
Tofacitinib Prodrug-1 is an effective and oral active prodrug to mitigate the systemic adverse effects of Tofacitinib. Tofacitinib Prodrug-1 can effectively attenuate the oxazolone-induced colitis in mice model with low ...
T31074 CP-690550A Tofacitinib metabolite M2,CP-690,550A,UNII-Q7ZOK859UK
Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.
T69957 Quoromycin
Quoromycin is a novel antivirulence agent against Vibrio vulnificus, inhibiting the quorum-sensing signaling pathway by controlling the DNA-binding affinity of SmcR and thus effectively alleviating the virulence of V. vu...
T70167 BP-5-087
BP-5-087 is a STAT3 inhibitor, combining with BCR-ABL1 inhibition to overcome kinase-independent resistance in chronic myeloid leukemia.
TargetMol