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Search Results for " tlr1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T13932 TLR1 Others , MyD88
TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
T15017 CU-T12-9 TLR
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...
T15020 CU-CPT22 TLR
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 μM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) ...
TP1067 Pam3CSK4 TFA (112208-00-1 free base) Pam3CSK4 TFA,Pam3Cys-Ser-(Lys)4 TFA TLR
Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).
T35672 SMU127
SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer.1It induces NF-κB signaling in cells expressing human TLR2 (EC50= 0.55 μM) but not cells expressing human TLR3, -4, -5, -7, or -8 when used at conce...
TP1066 Pam3CSK4-Biotin Pam3Cys-Ser-(Lys)4-Biotin
Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.
T74890 Diprovocim-X
Diprovocim-X (compound 35), a robust TLR1/TLR2 (toll-like receptor 1/2) agonist, exhibits EC 50 values of 0.14 nM for hTLR1/TLR2 and 0.75 nM for mTLR1/TLR2. As a potent in vivo adjuvant in mice, it effectively stimulates...
T37722 Diprovocim-1
Diprovocim-1 is an agonist of the toll-like receptor 1/2 heterodimer.1It induces TNF-α release in THP-1 cells (EC50= 110 pM), an effect that can be inhibited by anti-TLR1 or anti-TLR2 antibodies. Diprovocim-1 (10 mg/kg) ...
T83895 NCI 126224 NSC 126224
NCI 126224, a toll-like receptor 4 (TLR4) antagonist, demonstrates selective inhibition of nitric oxide (NO) production in RAW 264.7 macrophages, triggered by the TLR4 agonist LPS (IC50 = 0.31 µM), as opposed to minimal ...
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