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Pam3CSK4 TFA (112208-00-1 free base)

Catalog No. TP1067   CAS 112208-01-2
Synonyms: Pam3CSK4 TFA, Pam3Cys-Ser-(Lys)4 TFA

Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Pam3CSK4 TFA (112208-00-1 free base) Chemical Structure
Pam3CSK4 TFA (112208-00-1 free base), CAS 112208-01-2
Pack Size Availability Price/USD Quantity
1 mg In stock $ 128.00
5 mg In stock $ 302.00
10 mg In stock $ 453.00
25 mg In stock $ 761.00
50 mg In stock $ 997.00
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Purity: 96.4%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).
In vitro Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1]. Species differences were seen between the responses to Pam2CSK4 and Pam3CSK4 at TLR2/1. Pam3CSK4 (1 μg/mL) enhances the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils to Methicillin-resistant Staphylococcus aureus (MRSA)[2].
Synonyms Pam3CSK4 TFA, Pam3Cys-Ser-(Lys)4 TFA
Molecular Weight 1852.33
Formula C87H159F9N10O19S
CAS No. 112208-01-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Soluble

TargetMolReferences and Literature

1. Irvine KL, et al. The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6. Vet Res. 2013 Jul 4;44:50.

Related compound libraries

This product is contained In the following compound libraries:
Peptide Compound Library Immunology/Inflammation Compound Library NO PAINS Compound Library

Related Products

Related compounds with same targets
LHC-165 Afimetoran TLR7 agonist 2 TH1020 IAXO-102 SM360320 Bropirimine MD2-TLR4-IN-1

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Keywords

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