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Search Results for " tbk-1/ikkε-in-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T7951 TBK1/IKKε-IN-5 IκB/IKK
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
T15559 TBK1/IKKε-IN-2 IκB/IKK
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
T13097 TBK1/IKKε-IN-1 IκB/IKK
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
T39841 TBK1/IKKε-IN-6 TBK1/IKKε-IN-6
TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.
T38263 TBK1/IKKε-IN-4 TBK1/IKKε-IN-4
TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ...
T36994 MRT 67307 dihydrochloride SIK
MRT 67307 dihydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 dihyd...
T0097 MRT67307 MRT67307 HCl IκB/IKK , Autophagy
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...
T23028 MRT67307 HCl (1190378-57-4 free base) MRT67307 HCl Others
MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i...
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