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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T34775 | TAK285-Iodo | TAK-285-Iodo,TAK 285-Iodo,TAK285 derative | |
TAK285-IODO, similar to TAK285 in which the trifluoro group is replaced by iodo, is a novel dual erbB protein kinase inhibitor that specifically targets human epidermal growth factor receptor (EGFR) and HER2. | |||
T6039 | TAK-285 | TAK285,TAK 285 | EGFR , MEK , HER , Aurora Kinase |
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1. |