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Search Results for " sonidegib "

5

Compounds

Cat No. Product Name Synonyms Targets
T1926 Sonidegib Erismodegib,NVP-LDE225,LDE225 Hedgehog/Smoothened , Smo
Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
T15727 Sonidegib diphosphate NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate Smo
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively).
T20723 LGE-899 Sonidegib metabolite M48,LGE 899 Drug Metabolite
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.
T70178 Sonidegib metabolite M25
Sonidegib metabolite M25 is a smoothened (SMO) antagonist.
T32828 LNC-119 Sonidegib metabolite M16,LNC119
LNC-119 is an aminosteroid.
TargetMol