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Search Results for " schistosoma "

9

Compounds

Cat No. Product Name Synonyms Targets
T0272 Nilutamide RU23908 Androgen Receptor
Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...
T12770 RR-11a analog aza-peptide Michael acceptor, 7a Parasite
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, r...
T69421 Hydrolapachol
Hydrolapachol is a novel potent and selective inhibitor of schistosoma mansoni dihydroorotate dehydrogenase (smdhodh)
T34809 Teroxalene hydrochloride Teroxalene HCl,NSC 138704
Teroxalene Hydrochloride is disubstituted piperazine used to treat animals with Schistosoma mansoni.
T33957 PF-Alkyne PF Alkyne
PF-Alkyne is a fluorophosphonate-based probe which specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag. PF-Alkyne rapidly and site-selectively immobilizes sjGST f...
T61549 HDAC8-IN-2
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and ...
T61538 Antiparasitic agent-10
Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Sc...
T78619 Z-Pro-Pro-CHO Prolyl Endopeptidase (PREP)
Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01 μM for Schistosoma mansoni prolyl oligopeptidase [1].
T78391 DAUDA
DAUDA (11-(dansylamino)undecanoic acid), an environment-sensitive fluorescent fatty acid analogue, exhibits changes in fluorescent emission spectra and intensities upon interaction with binding proteins. This property of...
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