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Search Results for " ssb "

11

Compounds

Cat No. Product Name Synonyms Targets
T16807 Rucaparib monocamsylate Rucaparib Camsylate PARP
Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
T4463 Rucaparib AG-14447,PF-01367338,AG014699 PARP
Rucaparib (PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP.
T6127 Rucaparib Phosphate AG-014699 phosphate,PF-01367338,AG-014699,PF-01367338 phosphate PARP
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
T8440 LASSBio-1135 TNF , TRP/TRPV Channel
LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.
T24389 LASSBio-1366 LASSBio 1366
LASSBio-1366 is an agonist of adenosine A2a receptor that acts by attenuating the progression of monocrotaline-induced pulmonary hypertension.
T32582 LASSBio-881 LASSBio881,LASSBio 881
LASSBio-881 is a non-selective partial agonist of the CB1 and CB2 cannabinoid receptors, as well as an antagonist of the TRPV1 receptor.
T70164 LASSBio-1829 HCl
LASSBio-1829 HCl is an orally active IKK2 inhibitor.
T61794 LASSBio-1632
LASSBio-1632 is a novel anti-asthmatic lead candidate that selectively inhibits PDE4A and PDE4D isoenzymes, leading to the suppression of airway hyper-reactivity (AHR) and TNF-α production in lung tissue. With high exper...
T24388 LASSBio-1359 LASSBio1359,LASSBio 1359
LASSBio-1359 is an adenosine receptor agonist. It acts by inducing relaxation of the corpus cavernosum. It also acts as a novel selective phosphodiesterase.
T9430 Venadaparib NOV140101,IDX-1197 PARP
Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the...
T9756 AZD-9574 PARP
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.
TargetMol