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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12897L | SHIN1 | RZ-2994 | Others |
SHIN1 (RZ-2994) is an inhibitor of human serine hydroxymethyltransferse 1(SHMT1) with IC50 of 5 nM and human serine hydroxymethyltransferse 2 (SHMT2) with an IC50 of 13 nM. | |||
T62404 | SHMT-IN-2 | Others | |
SHMT-IN-2 (compound 2) is a specific human SHMT1/2 small molecule inhibitor that acts on SHMT1 (IC50: 13 nM) and SHMT2 (IC50: 66 nM). SHMT-IN-2 inhibits the growth of many human cancer cells and is sensitive to B-cell ly... | |||
T12898 | (+)-SHIN1 | (+)-RZ-2994 | Others |
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor. | |||
T41297 | Lometrexol hydrate | ||
Lometrexol hydrate (DDATHF hydrate) is an antipurine antifolate compound that inhibits glycinamide ribonucleotide formyltransferase (GARFT) activity without inducing detectable DNA strand breaks. It further disrupts de n... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00484 | SHMT1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to g... |