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Search Results for " shmt1 "

Targets

4

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12897L SHIN1 RZ-2994 Others
SHIN1 (RZ-2994) is an inhibitor of human serine hydroxymethyltransferse 1(SHMT1) with IC50 of 5 nM and human serine hydroxymethyltransferse 2 (SHMT2) with an IC50 of 13 nM.
T62404 SHMT-IN-2 Others
SHMT-IN-2 (compound 2) is a specific human SHMT1/2 small molecule inhibitor that acts on SHMT1 (IC50: 13 nM) and SHMT2 (IC50: 66 nM). SHMT-IN-2 inhibits the growth of many human cancer cells and is sensitive to B-cell ly...
T12898 (+)-SHIN1 (+)-RZ-2994 Others
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor.
T41297 Lometrexol hydrate
Lometrexol hydrate (DDATHF hydrate) is an antipurine antifolate compound that inhibits glycinamide ribonucleotide formyltransferase (GARFT) activity without inducing detectable DNA strand breaks. It further disrupts de n...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00484 SHMT1 Protein, Human, Recombinant (His) Human HEK293 Cells
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to g...
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