Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,470.00 | |
50 mg | 6-8 weeks | $ 1,920.00 |
Description | (+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. SHIN1 is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor. |
In vitro | (+)-SHIN1 ((+)-RZ-2994) is potent against cytosolic SHMT1 with growth-blocking IC50s for of less than 50 nM and 870 nM in SHMT2 deletion cells and HCT-116 cells, respectively [1]. |
Synonyms | (+)-RZ-2994 |
Molecular Weight | 400.47 |
Formula | C24H24N4O2 |
CAS No. | 2443966-90-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (249.71 mM)
You can also refer to dose conversion for different animals. More
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(+)-SHIN1 2443966-90-1 Others (+)SHIN1 SHIN1 RZ-2994 (+) SHIN1 RZ2994 RZ 2994 (+)-RZ-2994 SHIN 1 (+)-SHIN-1 SHIN-1 inhibitor inhibit