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Search Results for " sf-1 "

14

Compounds

Cat No. Product Name Synonyms Targets
T34686 Sonoflora 1 SF 1,SF-1,Sonoflora1,Sonoflora-1,SF1
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Precli...
T12075 ML-180 SR1848 Others
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .
T7687 AC 45594 4-Heptyloxyphenol Others
AC 45594 (4-Heptyloxyphenol) is an agonist of steroidogenic factor 1 (SF-1) ( IC50 : 50-100 nM)
T64363 (Iso)-RJW100 Others
(Iso)-RJW100 is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC 50 s of 6.4 and 7.2, respectively.
T38680 RJW100 Others
RJW100 is a compound that acts as a potent agonist of liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1), exhibiting pEC50 values of 6.6 and 7.5, respectively. Additionally, RJW100 induces r...
T23354 SID 7969543 Others
Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor
T62757 SID7970631
SID7970631 is an isoquinolinone analogue, a selective and potent submicromolar SF-1 inhibitor with an IC50 of 260 nM. SID7970631 can be used to study cancer.
T79411 HCAXII-IN-7 Carbonic Anhydrase
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability. Moreover, it promotes apoptosis in 786-0, SF-539, and HS 578 T cell line...
T75865 Neuropeptide SF(mouse,rat) TFA
Neuropeptide SF (mouse, rat) TFA, a potent agonist for neuropeptide FF receptors, exhibits K_i values of 48.4 nM for NPFF1 and 12.1 nM for NPFF2. Additionally, this compound enhances the amplitude of the sustained curren...
T61723 SS-RJW100
SS-RJW100 is an enantiomer of RJW100, known as a racemic agonist that targets two nuclear receptors: liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). In vitro experiments reveal that SS-RJW100 promotes...
T73231 RR-RJW100
RR-RJW100, an enantiomer of RJW100, functions as an agonist for both nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). Among its two synthesized enantiomers, RR-RJW100 and SS-RJW100, th...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...
T79706 TRK-IN-24 Trk receptor
TRK-IN-24 (compound 10g) is a selective inhibitor of Trk receptors, effectively targeting TRKA, TRKC, and mutant forms TRKA G595R, TRKA G667C, and TRKA F589L, with IC50 values of 5.21, 4.51, 6.77, 1.42, and 6.13 nM, resp...
T38069 Aquastatin A
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC...
TargetMol