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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12839 | SARS-CoV-IN-3 | Others | |
SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor. | |||
T60538 | SARS-CoV-2-IN-14 | 3',5-Dichlorosalicylanilide | SARS-CoV |
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzym... | |||
T78725 | SARS-CoV-2 nsp14-IN-3 | SARS-CoV | |
SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor targeting the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value of 3.5 μM [1]. | |||
T63679 | SARS-CoV-2 3CLpro-IN-3 | ||
SARS-CoV-2 3CLpro-IN-3 is a SARS CoV-2 3CLpro inhibitor that exhibits antiviral, antibacterial, and antifungal effects. | |||
T62375 | SARS-CoV-2 nsp13-IN-3 | ||
SARS-CoV-2 nsp13-IN-3 (Compound C3) is a small molecule inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on nsp13 ssDNA+ATPase (IC50: 32 μM). | |||
T8498 | EIDD-1931 | Beta-d-N4-hydroxycytidine | Virus Protease , HCV Protease , SARS-CoV , Topoisomerase |
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr... | |||
T60095 | CCF0058981 | SARS-CoV | |
CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-... | |||
T60686 | SARS-CoV-2 Mpro-IN-1 | ||
SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible SARS-CoV-2 main protease (Mpro) inhibitor (IC 50 = 116 nM) [1]. | |||
T63694 | SARS-CoV-2-IN-33 | ||
SARS-CoV-2-IN-33 is an inhibitor of COVID-19. SARS-CoV-2-IN-3 exhibits good binding affinity (-8.0 Kcal/mole) for COVID-19 major protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 exhibits good anti-proliferative effects o... | |||
T79245 | SARS-CoV-2-IN-45 | SARS-CoV | |
SARS-CoV-2-IN-45 (Compound 8p) serves as an inhibitor of SARS-CoV-2, effectively hindering viral replication in Calu-3 cells with an EC50 value of 0.5 μM and exhibiting negligible cytotoxic effects [1]. | |||
T62829 | SARS-CoV-2 nsp14-IN-1 | ||
SARS-CoV-2 nsp14-IN-1 (Compound 3) is a typical dual-substrate inhibitor of SARS-CoV-2Nsp14 Mtase (IC50: 0.061 μM). Histone lysine, protein arginine, DNA and RNA, etc.). | |||
T81209 | SARS-CoV-2-IN-62 | SARS-CoV | |
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1]. | |||
T79244 | SARS-CoV-2-IN-44 | SARS-CoV | |
SARS-CoV-2-IN-44, an inhibitor of SARS-CoV-2, effectively suppresses viral replication with an EC50 value of 0.6μM and exhibits negligible cytotoxicity in Calu-3 cells, rendering it suitable for antiviral research [1]. | |||
T81206 | SARS-CoV-2-IN-65 | SARS-CoV | |
SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRSS2 activity within the ACE2-dependent pathway in Calu-3 cel... | |||
T72451 | SARS-CoV-2 Mpro-IN-6 | ||
SARS-CoV-2 Mpro-IN-6 is a selective, covalent, and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an inhibition concentration (IC50) of 0.18 μM. It does not inhibit human cathepsins B, F, K, and L ... | |||
T81208 | SARS-CoV-2-IN-63 | SARS-CoV | |
SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal e... | |||
T73963 | Hydroxychloroquine Impurity E | ||
Hydroxychloroquine Impurity E, an impurity found in Hydroxychloroquine, a synthetic antimalarial compound that also inhibits Toll-like receptor 7/9 (TLR7/9) signaling, has been shown to effectively inhibit SARS-CoV-2 inf... | |||
T38174 | Mpro inhibitor N3 hemihydrate | ||
Mpro inhibitor N3 hemihydrate is a potent antagonist of the SARS-CoV-2 main protease (Mpro), demonstrating an EC50 of 16.77 μM against SARS-CoV-2. It exhibits specific inhibition of Mpro in a range of coronaviruses, incl... | |||
T69035 | Camostat free base | ||
Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or... | |||
T73964 | Hydroxychloroquine Impurity F | ||
Hydroxychloroquine Impurity F, an impurity in Hydroxychloroquine, is identified in the synthetic antimalarial agent known for its capability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Additionally, Hydroxychlo... |