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Search Results for " sar405 "

3

Compounds

Cat No. Product Name Synonyms Targets
T12831L SAR405 PI3K , Autophagy
SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor (IC50:1.2 nM; Kd:1.5 nM) that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by sta...
T12831 SAR405 R enantiomer Others
SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.
T6585 SAR405838 MI773,MI 773,MI-77301,MI-773 Mdm2 , E1/E2/E3 Enzyme
MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
TargetMol