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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6308 | Stattic | STAT3 Inhibitor V | Apoptosis , STAT |
Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis. | |||
T72029 | CDK8-IN-13 | Apoptosis , CDK | |
CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity... |