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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5313 | Sobetirome | IACS-010759,QRX-431 | Thyroid hormone receptor(THR) |
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM). | |||
T27568 | IACS-010759 hydrochloride | IACS-010759 HCl,IACS-010759,IACS10759,IACS-10759,IACS 10759 | |
IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NA... | |||
T5337 | IACS-010759 | IACS-10759,IACS 10759,IACS10759 | Apoptosis , Others , Mitochondrial Metabolism |
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain. |