Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I in low nM range. IACS-10759 shows significant efficacy in multiple tumor indications both in vitro and in vivo.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 68.00 | |
5 mg | 5 days | $ 122.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 162.00 |
Description | IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I in low nM range. IACS-10759 shows significant efficacy in multiple tumor indications both in vitro and in vivo. |
Synonyms | IACS-010759 HCl, IACS-010759, IACS10759, IACS-10759, IACS 10759 |
Molecular Weight | 599.03 |
Formula | C25H26ClF3N6O4S |
CAS No. | 1807523-99-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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IACS-010759 hydrochloride 1807523-99-4 IACS 010759 hydrochloride IACS-010759 HCl IACS-010759 IACS010759 Hydrochloride IACS010759 IACS010759 hydrochloride IACS 010759 IACS10759 IACS-10759 IACS 10759 IACS 010759 Hydrochloride IACS-010759 Hydrochloride inhibitor inhibit