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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23450 | TCS PrP Inhibitor 13 | 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One | Others |
TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation. | |||
T38789 | BMS-984923 | ||
BMS-984923, a highly potent silent allosteric modulator (SAM) of mGluR5, demonstrates exceptional binding affinity (K i = 0.6 nM). Additionally, this compound possesses favorable oral bioavailability and blood-brain barr... | |||
T81312 | Ralzapastotug | AB-308 | |
Ralzapastotug (AB-308) is a monoclonal antibody that targets amino acids 106-126 of the prion protein PrP^C[1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03842 | PRNP/Prion Protein Protein, Human, Recombinant (hFc) | Human | HEK293 |
Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamen... |