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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0214 | Pioglitazone | U 72107 | Ferroptosis , PPAR |
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury. | |||
T0214L | Pioglitazone hydrochloride | U-72107E,AD 4833,U 72107A,Pioglitazone HCl | Ferroptosis , PPAR |
Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. | |||
T12479 | Pioglitazone-d4 | U 72107 D4 | Others |
Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ . | |||
T61836 | Pioglitazone potassium | ||
Pioglitazone potassium (U 72107) is an orally active and selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ). It demonstrates high affinity binding to the ligand-binding domain of PPARγ, with an... | |||
T20465 | Ketopioglitazone | Keto pioglitazone,Pioglitazone metabolite M3 | |
Ketopioglitazone is an active metabolite of pioglitazone. | |||
T27210 | DRX-065 | DRX 065,DRX065,deuterated R-enantiomer of pioglitazone | |
DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects,... | |||
T15736 | Leriglitazone | Hydroxypioglitazone | Others |
Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM). Leriglitazone PioOH is a PPARγ agonist, stab... | |||
T73842 | Leriglitazone hydrochloride | ||
Leriglitazone (Hydroxypioglitazone) hydrochloride, a pioglitazone metabolite, acts as a PPARγ agonist, effectively stabilizing the PPARγ activation function-2 (AF-2) co-activator binding surface to enhance co-activator b... | |||
T28542 | Rivoglitazone HCl | CI-1037,CI1037,CS011,CS-011,CI 1037 | |
Rivoglitazone, also known as CI-1037; CS-011; DE-101; R-119702; Rivo, is a peroxisome proliferator-activated receptor γ agonist (PARPγ agonist) potentially for the treatment of type 2 diabetes. Rivoglitazone has been sho... |