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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23133 | Pentamidine | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal | |
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. | |||
T1654 | Pentamidine isethionate | Pentamidine isethionate salt,Pentamidine diisethionate | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent. | |||
T23132 | Pentamidine dihydrochloride | MP-601205 dihydrochloride | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi... | |||
T28355 | Pentamidine dimesylate | ||
Pentamidine dimesylate is an inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53) in malignant melanoma (MM). Pentamidine dimesylate restores p53 tumor suppressor activity in vivo. | |||
T11553 | Heptamidine dimethanesulfonate | SBi4211 dimethanesulfonate | Others |
Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) serves as a potent inhibitor related to Pentamidine, targeting the calcium-binding protein S100B with a dissociation constant (Kd) of 6.9 µM. It demonstrates sp... | |||
T11553L | Heptamidine | SBi4211 | Others |
Heptamidine is an effective Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM). It selectively kills melanoma cells with S100B over those without S100B. It is a useful tool for the investigat... |