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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79049 | Tegeprotafib | PTPN2/1-IN-1 | Phosphatase |
Tegeprotafib (PTPN2/1-IN-1) (Compound 124) is an orally active inhibitor targeting both PTPN2 and PTPN1B, displaying potent IC50 values at 4.4 nM for PTPN2 and 1-10 nM for PTPN1B, respectively [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPH-02277 | PTPN11 Protein, Human, Recombinant (T253M & Q257L, His) | Human | E. coli |
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosph... | |||
TMPY-03548 | PTPN12 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1. | |||
TMPY-03486 | PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) | Human | Baculovirus Insect Cells |
PTPN12 Protein, Human, Recombinant (aa 1-355, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.4 kDa and the accession number is AAA36529.1. |