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Search Results for " phgdh "

9

Compounds

Cat No. Product Name Synonyms Targets
T23150 PHGDH-inactive Others
inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503
T73143 PHGDH-IN-3 Dehydrogenase
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about cancer.
T62232 PHGDH-IN-2
PHGDH-IN-2 is a potent inhibitor of NAD+-competitive PHGDH (IC50: 5.2 μM). PHGDH-IN-2 exhibits inhibitory effects on the growth of PHGDH-dependent cancer cells and inhibits the serine synthesis pathway in MDA-MB-468 cell...
T4213 NCT-503 NCT 503 Dehydrogenase , FLT , TAM Receptor
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.
T16277 NCT-502 N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide Dehydrogenase
NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-d...
T14884 CBR-5884 Others , Dehydrogenase
CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with h...
T31557 DNS-pE DNSpE,DNS pE
DNS-pE is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
T28425 PKUMDL-WQ-2201
PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.
T14564 BI-4924 Others
BI-4924 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM). It has excellent Microsomal and hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis at 72 h ( IC50: 2200 nM...
TargetMol