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Cat No. | Product Name | Synonyms | Targets |
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T41267 | PROTAC(H-PGDS)-7 | ||
PROTAC(H-PGDS)-7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. PROTAC(H-PGDS)-... | |||
T1866 | AT-56 | Others , PGE Synthase | |
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects. | |||
T7948 | HPGDS inhibitor 2 | GSK-2894631A | PGE Synthase |
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm. | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T2681 | HPGDS-IN-1 | PGE Synthase | |
hPGDS-IN-1 is a hPGDS inhibitor. | |||
T61250 | HPGDS inhibitor 3 | ||
HPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally re... | |||
T69730 | F092 | PGE Synthase | |
F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases. | |||
T15503 | HQL-79 | Others | |
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no ... | |||
T38350 | TAS 205 | ||
TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS ... | |||
T38306 | Tetranor-PGDM | ||
Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222. | |||
TMPJ-00690 | PGDS Protein, Human, Recombinant | Human | E. coli |
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph... | |||
TMPY-04624 | Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1. | |||
TMPY-04077 | HPGDS/PGD2 Protein, Human, Recombinant (His) | Human | E. coli |
HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760. |