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Search Results for " pfkf "

Targets

4

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T67874 PFKFB3-IN-2 Glucokinase
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo.
T14365 AZ PFKFB3 26 Glucokinase
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.
T26730 AZ-PFKFB3-67
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3.
T62894 AZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM).

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05160 PFKP Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis ...
TMPJ-00868 PFKFB1 Protein, Human, Recombinant (His) Human HEK293 Cells
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate...
TMPY-04474 PFKFB3 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein wa...
TMPJ-00319 PFKFB3 Protein, Human, Recombinant (His) Human E. coli
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls the activity of the...
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