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Search Results for " oxphos-in-1 "

7

Compounds

Cat No. Product Name Synonyms Targets
T62890 OXPHOS-IN-1
OXPHOS-IN-1 (compound 2) is an inhibitor of oxidative phosphorylation (OXPHOS) and inhibits the growth of MIA PaCa-2 cells (IC50: 2.34 μM) and BxPC-3 cells (IC50: 13.82 μM).
T8532 IM156 OXPHOS
IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in anima...
T74092 Cyanine5 alkyne
Cyanine5 alkyne (Alkyne-Cy5), a fluorescent dye, labels azide proteins for analyzing post-translational modifications, such as glycosylation. Additionally, it serves as a mitochondrial OXPHOS inhibitor, curtailing the pr...
T79226 AMPK activator 11 Mitochondrial Metabolism
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...
T79286 TRAP1-IN-2 HSP
TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients. It inhibits oxidative phosphorylation (OXPHOS) and shifts cellular metabolism towar...
T79285 TRAP1-IN-1 HSP
TRAP1-IN-1 (compound 35) is a potent, selective TRAP1 inhibitor affecting the mitochondrial variant of Hsp90. It exhibits over 250-fold greater selectivity for TRAP1 compared to Grp94, destabilizes TRAP1 tetramers, and p...
T75656 Calcimycin hemimagnesium
Calcimycin (A-23187) hemimagnesium, an antibiotic and divalent cation ionophore (such as calcium and magnesium), serves various biological roles. It triggers Ca2+-dependent cell death by elevating intracellular calcium l...
TargetMol