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Search Results for " nsclcs "

3

Compounds

Cat No. Product Name Synonyms Targets
T11569 HKI-357 EGFR
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
TQ0219 MK-8033 c-Met/HGFR
MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).
T1181 Gefitinib ZD1839 EGFR , Tyrosine Kinases , Autophagy
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...
TargetMol