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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40187 | GNF2133 | DYRK | |
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes. | |||
T63040 | GNF2133 hydrochloride | ||
GNF2133 hydrochloride is a selective, effective, and orally active DYRK1A inhibitor, able to act on DYRK1A (IC50: 0.0062 μM) and GSK3β (IC50> 50 μM); GNF2133 hydrochloride showed good proliferative ability and efficacy i... | |||
TP2274 | NF279 | NF 279 | Others |
P2X1 antagonist | |||
T79446 | INF200 | NOD-like Receptor (NLR) | |
INF200 (compound 5), a sulfonylurea-based inhibitor of NLRP3 and associated pyroptosis, exhibits cardiometabolic benefits in a rat model of high-fat diet (HFD)-induced metaflammation and demonstrates anti-inflammatory ef... | |||
T69638 | VT-105 | VT 105 | Others |
VT-105 is a potent and selective TEAD autopalmitoylation inhibitor that inhibits proliferation and tumour growth in NF2-deficient mesotheliomas. | |||
T79428 | AF-2112 | YAP | |
AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2. | |||
T71424 | VT-102 free base | ||
VT-102 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT102 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect... | |||
T68934 | VT101 free base | ||
VT101 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT101 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect ... | |||
T79427 | LM-41 | YAP | |
LM-41, a Flufenamic acid-derived TEAD inhibitor, significantly reduces the expression of CTGF, Cyr61, Axl, and NF2, and inhibits the migration of human MDA-MB-231 breast cancer cells [1]. |