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Search Results for " nf2 "

9

Compounds

Cat No. Product Name Synonyms Targets
T40187 GNF2133 DYRK
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
T63040 GNF2133 hydrochloride
GNF2133 hydrochloride is a selective, effective, and orally active DYRK1A inhibitor, able to act on DYRK1A (IC50: 0.0062 μM) and GSK3β (IC50> 50 μM); GNF2133 hydrochloride showed good proliferative ability and efficacy i...
TP2274 NF279 NF 279 Others
P2X1 antagonist
T79446 INF200 NOD-like Receptor (NLR)
INF200 (compound 5), a sulfonylurea-based inhibitor of NLRP3 and associated pyroptosis, exhibits cardiometabolic benefits in a rat model of high-fat diet (HFD)-induced metaflammation and demonstrates anti-inflammatory ef...
T69638 VT-105 VT 105 Others
VT-105 is a potent and selective TEAD autopalmitoylation inhibitor that inhibits proliferation and tumour growth in NF2-deficient mesotheliomas.
T79428 AF-2112 YAP
AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.
T71424 VT-102 free base
VT-102 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT102 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect...
T68934 VT101 free base
VT101 is a TEAD Auto-palmitoylation inhibitor that Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT101 inhibited the firefly luciferase reporter dose-dependently and had no 204 effect ...
T79427 LM-41 YAP
LM-41, a Flufenamic acid-derived TEAD inhibitor, significantly reduces the expression of CTGF, Cyr61, Axl, and NF2, and inhibits the migration of human MDA-MB-231 breast cancer cells [1].
TargetMol