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Search Result

Search Results for " mst1 "

Targets

Hippo pathway

3

Compounds

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T62512 IHMT-MST1-58 Hippo pathway
IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity. IHMT-MST1-58 can be used to study type 1 or type 2 diabetes.
T4212 XMU-MP-1 Hippo pathway
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.
T9470 HPK1-IN-7 MAPK
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).

Recombinant Proteins

Species：
Human (6)
Expression System：
E. coli (4)
Baculovirus Insect Cells (1)
P. pastoris (Yeast) (1)
Tag：
N-6xHis (2)
GST (1)
His (1)
N-10xHis, C-Myc (1)
N-6xHis-SUMO (1)
Cat No. Product Name Species Expression System
TMPY-04398 MST1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The t...
TMPY-03442 MOB4A/MOB1B Protein, Human, Recombinant (GST) Human E. coli
MST1 and MST2 are the mammalian Ste2-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. Overexpression of MST1 or MST2 in mammalian ...
TMPH-02226 TEAD3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-02225 TEAD2 Protein, Human, Recombinant (His & Myc) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-02222 TEAD1 Protein, Human, Recombinant (His) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
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