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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13782 | MS432 | MEK | |
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2. | |||
T82378 | Folate-MS432 | PROTACs | |
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways. | |||
T17638 | Boc-11-aminoundecanoic acid | Others , PROTAC Linker | |
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker that can be used in the synthesis of MS432. | |||
T40233 | (Iso)-MS4322 | (Iso)-YS43-22,MS4322 (isomer),YS43-22 (isomer) | Histone Methyltransferase |
(Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits th... | |||
T17694 | Br-C10-methyl ester | Others , PROTAC Linker | |
Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a lin... | |||
T18668 | (S,R,S)-AHPC-Me-C10-Br | Others | |
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1]. | |||
T18669 | (S,R,S)-AHPC-Me-C10-NH2 | Others | |
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in ... |