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Search Results for " ms432 "

7

Compounds

Cat No. Product Name Synonyms Targets
T13782 MS432 MEK
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.
T82378 Folate-MS432 PROTACs
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.
T17638 Boc-11-aminoundecanoic acid Others , PROTAC Linker
Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker that can be used in the synthesis of MS432.
T40233 (Iso)-MS4322 (Iso)-YS43-22,MS4322 (isomer),YS43-22 (isomer) Histone Methyltransferase
(Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits th...
T17694 Br-C10-methyl ester Others , PROTAC Linker
Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a lin...
T18668 (S,R,S)-AHPC-Me-C10-Br Others
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1].
T18669 (S,R,S)-AHPC-Me-C10-NH2 Others
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in ...
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